IMMUNOSUPPRESSIVE THERAPY OF AUTOIMMUNE-DISEASES

被引：12
作者：
BACH, JF
机构：
[1] Hôpital Necker, 75743 Paris Cedex 15
来源：
TRENDS IN PHARMACOLOGICAL SCIENCES | 1993年 / 14卷 / 05期
关键词：
D O I：
10.1016/0165-6147(93)90211-2
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Ciclosporin and cyclophosphamide show a remarkable efficacy in most autoimmune diseases. However, their effect is dependent on continuous drug administration with risks of drug toxicity and over immunosuppression. Results recently obtained in animal models, discussed here by Jean Francois Bach particularly with anti-CD3 and anti-CD4 monoclonal antibodies, indicate that reestablishment of tolerance to self antigens is a feasible goal.
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收藏
页码：213 / 216
页数：4
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