AMINO-ACID TRANSFORMATION .7. CHEMOENZYMATIC SYNTHESES OF OMEGA-UREIDO D-AMINO ACIDS

被引：16

作者：

DRAUZ, K

KOTTENHAHN, M

MAKRYALEAS, K

KLENK, H

BERND, M

机构：

[1] Degussa AG, Fachbereich Organische und Biologische Chemie, Hanau, W-6450

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1991年 / 30卷 / 06期

关键词：

D O I：

10.1002/anie.199107121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

D-Amino acids can be prepared chemoenzymatically in very high yields with high enantioselectivity by cleavage of the corresponding hydantoins with Agrobacterium radiobacter bacterial culture. Hydantoins with highly functionalized side chains are also accepted. The synthetic concept is discussed taking D-citrulline (1) as example.

引用

页码：712 / 714

页数：3

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