THE SENSITIVITY, SPECIFICITY AND EFFICIENCY VALUES OF SOME SEROLOGICAL TESTS USED IN THE DIAGNOSIS OF PARACOCCIDIOIDOMYCOSIS

被引：45

作者：

DELNEGRO, GMB ^{[1
]}

GARCIA, NM ^{[1
]}

RODRIGUES, EG ^{[1
]}

CANO, MIN ^{[1
]}

DEAGUIAR, MSM ^{[1
]}

LIRIO, VD ^{[1
]}

LACAZ, CD ^{[1
]}

机构：

[1] INST MED TROP SAO PAULO,MICOL MED LAB,SAO PAULO,BRAZIL

来源：

REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO | 1991年 / 33卷 / 04期

关键词：

PARACOCCIDIOIDOMYCOSIS; PARACOCCIDIOIDES-BRASILIENSIS; SEROLOGICAL TESTS;

D O I：

10.1590/S0036-46651991000400006

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This work reports on the results of double immunodiffusion (ID), counterimmunoelectrophoresis (CIE), complement fixation (CF) and indirect immunofluorescence (IIF) techniques in the serodiagnosis of paracoccidioidomycosis. The study was undertaken on four groups of individuals: 46 patients with untreated paracoccidioidomycosis, 22 patients with other deep mycoses, 30 with other infectious diseases (tuberculosis and cutaneous leishmaniasis) and 47 blood donors as negative controls. Data were obtained using Paracoccidioides brasiliensis antigens, i.e., a yeast culture filtrate for ID, CIE and CF, and a yeast cell suspension for IIF. The sensitivity, specificity and efficiency values were measured according to GALEN & GAMBINO8. The gel precipitation tests (ID and CIE) showed the greatest sensitivity (91.3 and 95.6%, respectively), maximum specificity (100%) and the highest efficiency values when compared to the CF and IIF tests.

引用

页码：277 / 280

页数：4

共 16 条

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