ANTISECRETORY ACTIONS OF AMINOPHYLLINE IN THE RAT AND DOG

被引：2

作者：

JACOBY, HI

BONFILIO, AC

GRAY, S

STAUS, A

THOMAS, C

机构：

来源：

DIGESTION | 1979年 / 19卷 / 04期

关键词：

D O I：

10.1159/000198351

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The effect of aminophylline on gastric acid secretion has been studied in the rat and dog. Aminophylline was shown to possess antisecretory activity when given either by oral or parenteral administration in an acute gastric fistula rat preparation. In the chronic gastric fistula dog aminophylline at 50 mg/kg intragastrically induced a small but significant stimulation of basal acid secretion. This dose of aminophylline also significantly inhibited acid secretion induced by gastrin tetrapeptide, and 2-deoxy-D-glucose but did not block acid secretion induced by histamine.

引用

页码：237 / 243

页数：7

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