DETECTION AND CLINICAL-SIGNIFICANCE OF MINIMAL TUMOR-CELL CONTAMINATION OF PERIPHERAL STEM-CELL HARVESTS

被引：109

作者：

SHARP, JG

KESSINGER, A

VAUGHAN, WP

MANN, S

CROUSE, DA

DICKE, K

MASIH, A

WEISENBURGER, DD

机构：

[1] UNIV NEBRASKA,MED CTR,DEPT INTERNAL MED,OMAHA,NE 68198

[2] UNIV NEBRASKA,MED CTR,DEPT PATHOL & MICROBIOL,OMAHA,NE 68198

来源：

INTERNATIONAL JOURNAL OF CELL CLONING | 1992年 / 10卷

关键词：

TUMOR CELL CULTURES; PERIPHERAL STEM CELL TRANSPLANTATION;

D O I：

10.1002/stem.5530100731

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Peripheral stem cell (PSC) harvests from patients with non-Hodgkin's lymphoma (NHL) and breast cancer are less likely to be contaminated with occult tumor cells detected by culture techniques, than are bone marrow harvests. Clinically, NHL patients transplanted with such PSC harvests had a better outcome than recipients of bone marrow harvests.

引用

页码：92 / 94

页数：3