CDNA CLONING OF HUMAN CYTOSOLIC PLATELET-ACTIVATING-FACTOR ACETYLHYDROLASE GAMMA-SUBUNIT AND ITS MESSENGER-RNA EXPRESSION IN HUMAN TISSUES

被引：39

作者：

ADACHI, H ^{[1
]}

TSUJIMOTO, M ^{[1
]}

HATTORI, M ^{[1
]}

ARAI, H ^{[1
]}

INOUE, K ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,DEPT HLTH CHEM,BUNKYO KU,TOKYO 113,JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 214卷 / 01期

关键词：

D O I：

10.1006/bbrc.1995.2272

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cDNA for human cytosolic platelet-activating factor acetylhydrolase (PAF-AH) gamma-subunit was isolated and the gene structure was elucidated. The complete amino acid sequence deduced from cDNA contains 231 amino acid residues. Southern blot analysis indicated the presence of a single gene. Northern blot analysis showed that 1.0 kb transcript was expressed in a tissue specific manner. Comparison of the expression pattern between adult and fetal tissues suggests that the enzyme plays an important role during the development of brain. (C) 1995 Academic Press, Inc.

引用

页码：180 / 187

页数：8

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