FIRST EVIDENCE FOR HOMOLOGOUS RECOMBINATION-MEDIATED LARGE DNA INVERSION ON THE BACILLUS-SUBTILIS-168 CHROMOSOME

被引：7

作者：

ITAYA, M

机构：

[1] Mitsubishi Kasei Institute of Life Sciences, Machida-shi, Tokyo 194

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1994年 / 58卷 / 10期

关键词：

D O I：

10.1271/bbb.58.1836

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A Bacillus subtilis 168 strain carrying an inversion of about 1600 kb-long chromosomal DNA was isolated. Physical and genetic analyses demonstrated that the inversion was generated as a result of homologous recombination between two homologous sequences integrated at the met and leuB loci. This is the first clear evidence of a large stable chromosomal inversion induced by homologous recombination in B. subtilis.

引用

页码：1836 / 1841

页数：6

共 17 条

[1] ANAGNOSTOPOULOS C, 1990, BACTERIAL CHROMOSOME, P361
[2] WHEN POLYMERASES COLLIDE - REPLICATION AND THE TRANSCRIPTIONAL ORGANIZATION OF THE ESCHERICHIA-COLI CHROMOSOME
BREWER, BJ
[J]. CELL, 1988, 53 (05) : 679 - 686
[3] Dubnau D., 1982, MOL BIOL BACILLI, P147
[4] HILL CW, 1990, BACTERIAL CHROMOSOME, P335
[5] THE BLASTICIDIN-S RESISTANCE GENE (BSR) SELECTABLE IN A SINGLE COPY STATE IN THE BACILLUS-SUBTILIS CHROMOSOME
ITAYA, M
YAMAGUCHI, I
KOBAYASHI, K
ENDO, T
TANAKA, T
[J]. JOURNAL OF BIOCHEMISTRY, 1990, 107 (06) : 799 - 801
[6] INTEGRATION OF REPEATED SEQUENCES (PBR322) IN THE BACILLUS-SUBTILIS 168-CHROMOSOME WITHOUT AFFECTING THE GENOME STRUCTURE
ITAYA, M
[J]. MOLECULAR & GENERAL GENETICS, 1993, 241 (3-4): : 287 - 297
[7] COMPLETE PHYSICAL MAP OF THE BACILLUS-SUBTILIS 168-CHROMOSOME CONSTRUCTED BY A GENE-DIRECTED MUTAGENESIS METHOD
ITAYA, M
TANAKA, T
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1991, 220 (03) : 631 - 648
[8] STABILITY AND ASYMMETRIC REPLICATION OF THE BACILLUS-SUBTILIS 168 CHROMOSOME STRUCTURE
ITAYA, M
[J]. JOURNAL OF BACTERIOLOGY, 1993, 175 (03) : 741 - 749
[9] PHYSICAL MAPPING OF MULTIPLE HOMOLOGOUS GENES IN THE BACILLUS-SUBTILIS-168 CHROMOSOME - IDENTIFICATION OF 10 RIBOSOMAL-RNA OPERON LOCI
ITAYA, M
[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1993, 57 (09) : 1611 - 1614
[10] JARVIS ED, 1990, GENETICS, V126, P785

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