CHEMISTRY OF DIORGANOCUPRATES CONTAINING FUNCTIONALIZED LIGANDS .2. METHODOLOGY FOR CONJUGATE ADDITION OF SYNTHETIC EQUIVALENTS OF ENOLATES AND ACYL ANIONS

被引:46
作者
BOECKMAN, RK
BRUZA, KJ
机构
[1] Department of Chemistry, Wayne State University, Detroit
关键词
D O I
10.1021/jo00394a008
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Methodology is described by which several classes of masked synthons, the synthetic equivalents of acyl anions and enolates, can be rendered reactive as ligands in the corresponding diorganocuprate complexes. Vinyl ethers and vinylsilanes were studied, and a comparison of their reactivities, stabilities and unmasking characteristics is given. The two classes of reagents prove nicely complementary in terms of their spectrum of reactivity, selectivity, and ease in unmasking. © 1979, American Chemical Society. All rights reserved.
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页码:4781 / 4788
页数:8
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