EXPRESSION OF THE YEAST DNA PRIMASE GENE, PRI1, IS REGULATED WITHIN THE MITOTIC CELL-CYCLE AND IN MEIOSIS

被引：27

作者：

JOHNSTON, LH ^{[1
]}

WHITE, JHM ^{[1
]}

JOHNSON, AL ^{[1
]}

LUCCHINI, G ^{[1
]}

PLEVANI, P ^{[1
]}

机构：

[1] UNIV MILANO,DIPARTIMENTO GENET & BIOL MICRORGANISMI,I-20133 MILAN,ITALY

来源：

MOLECULAR & GENERAL GENETICS | 1990年 / 221卷 / 01期

关键词：

Cell cycle; DNA primase; Meiosis; Yeast;

D O I：

10.1007/BF00280366

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis. © 1990 Springer-Verlag.

引用

页码：44 / 48

页数：5

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