A QUANTITATIVE STUDY OF PHYSIOLOGICAL CEREBRAL ATROPHY WITH AGING - A STATISTICAL-ANALYSIS OF THE NORMAL RANGE

被引：40
作者：
NAGATA, K
BASUGI, N
FUKUSHIMA, T
TANGO, T
SUZUKI, I
KAMINUMA, T
KURASHINA, S
机构：
[1] TOKYO METROPOLITAN INST MED SCI,TOKYO 113,JAPAN
[2] MITSUI MEM HOSP,DEPT NEUROSURG,TOKYO 101,JAPAN
[3] KANTO ROSAI HOSP,DEPT NEUROSURG,KAWASAKI,JAPAN
来源：
NEURORADIOLOGY | 1987年 / 29卷 / 04期
关键词：
Aging; Cerebral atrophy; CT scan; Quantitative analysis;
D O I：
10.1007/BF00348909
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A new method of discriminating pathological cerebral atrophy from physiological atrophy during aging is reported. The authors advocate a pixel counting method using a minicomputer for the quantitative measurement of cerebral atrophy. Five hundred cases were studied with this quantitative method and the normal range of the physiological atrophy was determined statistically. In order to estimate the degree of cerebral atrophy easily, the conventional linear measurement methods were compared with the pixel counting method using multivariant analysis, and a simple formula for the calculation of the degree of cerebral atrophy is proposed. Using this formula and the normal range, pathological cerebral atrophy is easily detectable. © 1987 Springer-Verlag.
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页码：327 / 332
页数：6
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