LANGERHANS CELL HISTIOCYTOSIS AND THE NERVOUS-SYSTEM

被引：21
作者：
BURN, DJ
WATSON, JDG
RODDIE, M
CHU, AC
LEGG, NJ
FRACKOWIAK, RSJ
机构：
[1] UCL NATL HOSP NEUROL & NEUROSURG, LONDON, ENGLAND
[2] HAMMERSMITH HOSP, DEPT MED, NEUROL UNIT, LONDON W12 0HS, ENGLAND
[3] HAMMERSMITH HOSP, DEPT DIAGNOST RADIOL, LONDON W12 0HS, ENGLAND
[4] HAMMERSMITH HOSP, DEPT MED, DERMATOL UNIT, LONDON W12 0HS, ENGLAND
来源：
JOURNAL OF NEUROLOGY | 1992年 / 239卷 / 06期
关键词：
LANGERHANS CELL HISTIOCYTOSIS; CENTRAL NERVOUS SYSTEM;
D O I：
10.1007/BF00867593
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report two cases of Langerhans' cell histiocytosis with unusual central nervous system (CNS) involvement. The first patient had behavioural disturbances, memory loss and diabetes insipidus. His response to a range of treatments was poor. The second patient presented with seizures and headaches suggestive of raised intracranial pressure. Etoposide (VP16) chemotherapy led to a dramatic clinical and radiologicaL improvement. The various CNS manifestations of Langerhans' cell histiocytosis and their management are discussed.
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页码：345 / 350
页数：6
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