STABILITY OF ACETALDEHYDE IN HUMAN-BLOOD SAMPLES

被引：20

作者：

STOWELL, AR

BATT, RD

GREENWAY, RM

机构：

[1] Department of Chemistry, Biochemistry, and Biophysics, Massey University, Palmerston North

来源：

BIOCHEMICAL MEDICINE | 1978年 / 20卷 / 02期

关键词：

D O I：

10.1016/0006-2944(78)90064-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Acetaldehyde was found to disappear rapidly in human venous blood samples when added in concentrations ranging from 10 to 50 μm. The disappearance was dependent on temperature and the presence of blood cells. Evidence is presented for the conversion of acetaldehyde to acetate. By contrast, acetaldehyde which accumulates in human venous blood samples from the metabolism of ethanol in vivo did not disappear under conditions where added acetaldehyde disappeared rapidly. It is suggested that acetaldehyde formed from ethanol in vivo may be bound reversibly to blood constituents. © 1978.

引用

页码：167 / 179

页数：13

共 21 条

[1]

AMMON HPT, 1971, BIOLOGICAL ASPECTS A, P185

[2]

COUCHMAN KG, 1974, THESIS MASSEY U

[3]

DEITRICH RA, 1966, BIOCHEM PHARMACOL, V15, P1911

[4]

DURITZ G, 1964, Q J STUD ALCOHOL, V25, P498