GONADAL-STEROIDS AS PROMOTERS OF NEURO-GLIAL PLASTICITY

被引：68

作者：

GARCIASEGURA, LM ^{[1
]}

CHOWEN, JA ^{[1
]}

DUENAS, M ^{[1
]}

TORRESALEMAN, I ^{[1
]}

NAFTOLIN, F ^{[1
]}

机构：

[1] YALE UNIV, SCH MED, DEPT OBSTET & GYNECOL, NEW HAVEN, CT 06510 USA

来源：

PSYCHONEUROENDOCRINOLOGY | 1994年 / 19卷 / 5-7期

关键词：

ESTRADIOL; PROGESTERONE; TROPHIC FACTORS; GABA; ASTROGLIA; SYNAPTIC PLASTICITY;

D O I：

10.1016/0306-4530(94)90031-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Estradiol induces coordinated modifications in the extension of glial and neuronal processes in the arcuate nucleus of the hypothalamus of adult female rats. This hormonal effect results in natural fluctuations in the ensheathing of arcuate neurons by glial processes and these glial changes are linked to a remodelling of inhibitory GABAergic synapses during the estrous cycle. Hormonally induced glial and synaptic changes appear to be dependent on specific recognition or adhesion molecules on the neuronal and/or glial membranes.

引用

页码：445 / 453

页数：9

共 63 条

[21]

JUNGTESTAS I, 1989, ENDOCRINOLOGY, V125, P2083

[22] PREGNENOLONE METABOLISM IN RODENT EMBRYONIC NEURONS AND ASTROCYTES [J].

KABBADJ, K ;

ELETR, M ;

BAULIEU, EE ;

ROBEL, P .

GLIA, 1993, 7 (02) :170-175

[23]

KOZLOWSKI GP, 1985, CELL TISSUE RES, V242, P301

[24] ESTROGEN RECEPTOR-IMMUNOREACTIVE GLIA, ENDOTHELIA, AND EPENDYMA IN GUINEA-PIG PREOPTIC AREA AND MEDIAN-EMINENCE - ELECTRON-MICROSCOPY [J].

LANGUB, MC ;

WATSON, RE .

ENDOCRINOLOGY, 1992, 130 (01) :364-372

[25] NATURAL FLUCTUATION AND GONADAL HORMONE REGULATION OF ASTROCYTE IMMUNOREACTIVITY IN DENTATE GYRUS [J].

LUQUIN, S ;

NAFTOLIN, F ;

GARCIASEGURA, LM .

JOURNAL OF NEUROBIOLOGY, 1993, 24 (07) :913-924

[26]

MA YJ, 1992, NEURON, V9, P657

[27] FUNCTIONAL RECEPTORS FOR VASOACTIVE INTESTINAL POLYPEPTIDE IN CULTURED ASTROGLIA FROM NEONATAL RAT-BRAIN [J].

MAGISTRETTI, PJ ;

MANTHORPE, M ;

BLOOM, FE ;

VARON, S .

REGULATORY PEPTIDES, 1983, 6 (01) :71-80

[28] NEUROSTEROIDS - ENDOGENOUS BIMODAL MODULATORS OF THE GABA-A RECEPTOR - MECHANISM OF ACTION AND PHYSIOLOGICAL SIGNIFICANCE [J].

MAJEWSKA, MD .

PROGRESS IN NEUROBIOLOGY, 1992, 38 (04) :379-395

[29] STEROID-HORMONE METABOLITES ARE BARBITURATE-LIKE MODULATORS OF THE GABA RECEPTOR [J].

MAJEWSKA, MD ;

HARRISON, NL ;

SCHWARTZ, RD ;

BARKER, JL ;

PAUL, SM .

SCIENCE, 1986, 232 (4753) :1004-1007

[30] SYNAPTOGENIC ACTION OF SEX STEROIDS IN DEVELOPING AND ADULT NEUROENDOCRINE BRAIN [J].

MATSUMOTO, A .

PSYCHONEUROENDOCRINOLOGY, 1991, 16 (1-3) :25-40

← 1 2 3 4 5 6 7 →