MULTICOMPARTMENT PHARMACOKINETIC ANALYSIS AND SIMULATIONS USING A PROGRAMMABLE CALCULATOR

被引：9

作者：

NIAZI, S

机构：

[1] Department of Pharmacy, College of Pharmacy, University of Illinois, Chicago

来源：

INTERNATIONAL JOURNAL OF BIO-MEDICAL COMPUTING | 1979年 / 10卷 / 03期

关键词：

1 compartment models; 2 compartment models; feathering technique; HP-97; log-linear regression; Programmable calculator; steady state plasma level estimation;

D O I：

10.1016/0020-7101(79)90015-1

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings. © 1979.

引用

页码：245 / 255

页数：11