EFFECT OF DESALIVATION ON WATER AND SODIUM-CHLORIDE INTAKE IN RATS

被引：1
|
作者：
NICHOLSON, TM [1 ]
ROWLAND, NE [1 ]
机构：
[1] UNIV FLORIDA,DEPT PSYCHOL,GAINESVILLE,FL 32611
来源：
PHYSIOLOGY & BEHAVIOR | 1994年 / 56卷 / 03期
基金：
美国国家科学基金会;
关键词：
RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (RAAS); SALIVARY GLANDS; THIRST; SODIUM APPETITE; CONVERTING ENZYME INHIBITOR (CEI); SPRAGUE-DAWLEY RATS; ISOPROTERENOL;
D O I：
10.1016/0031-9384(94)90299-2
中图分类号：
B84 [心理学];
学科分类号：
04 ; 0402 ;
摘要：
Desalivate rats consumed significantly less water than sham-operated rats in response to acute challenges with a variety of dipsogens, including polyethelene glycol (PEG), isoproterenol, serotonin, and an angiotensin I converting enzyme inhibitor (CEI). Nonsignificant reductions were recorded after treatments with either angiotensin II or hypertonic NaCl. Meal-related hyperdipsia, and resultant possible hyperhydration, of desalivate rats does not account fully for these reductions in experimental thirsts. The mean 24-h intake of three concentrations of NaCl, in choice with water, showed no difference in the preferences for NaCl of desalivate and sham-operated animals. During chronic administration of CEIs, both desalivate and sham-operated rats showed comparable induction of NaCl appetite.
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页码：543 / 547
页数：5
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