A CONVENIENT ENANTIOSELECTIVE SYNTHESIS OF TRANS-2-ARYLOXYCYCLOHEXAN-1-OLS USING PIG-LIVER ACETONE POWDER (PLAP) AS BIOCATALYST

被引：15
作者：
BASAVAIAH, D
KRISHNA, PR
BHARATHI, TK
机构：
[1] School of Chemistry, University of Hyderabad, Hyderabad
来源：
TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 02期
关键词：
D O I：
10.1016/0957-4166(95)00029-O
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Pig liver acetone powder (PLAP) has been used as a biocatalyst for enantioselective hydrolysis of racemic trans-1-acetoxy-2-aryloxycyclohexanes to produce the resulting (R,R)-2-aryloxycyclohexan-1-ols upto >99% enantiomeric purities. (R,R)-Selectivity in this hydrolysis of racemic trans-2-aryloxycyclohexyl acetates was explained on the basis of Jones' three dimensional active site-model.
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页码：439 / 454
页数：16
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