THEORETICAL-MODELS OF PHOSPHOLIPID PHASE-TRANSITIONS

被引：163

作者：

MOURITSEN, OG

机构：

[1] Department of Structural Properties of Materials, The Technical University of Denmark, DK-2800 Lyngby

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 1991年 / 57卷 / 2-3期

关键词：

PHOSPHOLIPID; BILAYER; PHASE TRANSITION; FLUCTUATIONS; LIPID-CHOLESTEROL INTERACTION; LIPID-PROTEIN INTERACTION; ANESTHETICS;

D O I：

10.1016/0009-3084(91)90075-M

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A brief review is given of the theoretical models and calculational methods used to study the main phase transition in phospholipid membranes with particular emphasis on recent progress. The models are discussed in terms of the mechanical variables and the various interactions which are necessary to describe the phase transition. Theoretical results are presented for the transitional properties and how the phase equilibria are affected by ''impurities'' such as cholesterol, proteins and anaesthetics.

引用

页码：179 / 194

页数：16

共 83 条

[1]

ABREY JR, 1985, PROGR PROTEIN LIPID, P1

[2] NATURE OF GEL TO LIQUID-CRYSTAL TRANSITION OF SYNTHETIC PHOSPHATIDYLCHOLINES [J].