N-(2-{[5-Bromo-2-(morpholin-4-yl)-pyrimidin-4-yl]sulfanyl}-4-methoxy-phenyl)-4-methylbenzenesulfonamide

In the title compound, C22H23BrN4O4S2, the benzene rings bridged by the sulfonamide group are tilted relative to each other by 68.9 (1)degrees and the dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 69.7 (1)degrees. The molecular conformation is stabilized by a weak intramolecular pi-pi stacking interaction between the pyrimidine and the 4-methylbenzene rings [centroid-centroid distance = 3.934 (2) angstrom]. The morpholine ring adopts a chair conformation and is disordered over two positions with an occupancy ratio of 0.853 (6):0.147 (6). In the crystal, molecules are linked by N-H center dot center dot center dot O hydrogen bonds into chains extending along the a axis and further, through C-H center dot center dot center dot N and C-H center dot center dot center dot O interactions, into a three-dimensional supramolecular structure.