CORRELATION BETWEEN ANTI-HBC TITERS AND HBV DNA IN BLOOD UNITS WITHOUT DETECTABLE HBSAG

被引：139
作者：
IIZUKA, H
OHMURA, K
ISHIJIMA, A
SATOH, K
TANAKA, T
TSUDA, F
OKAMOTO, H
MIYAKAWA, Y
MAYUMI, M
机构：
[1] JICHI MED SCH,DIV IMMUNOL,MINAMI KAWACHI,TOCHIGI 32904,JAPAN
[2] JAPANESE RED CROSS,SAITAMA BLOOD CTR,SAITAMA,JAPAN
[3] KITASATO INST,IMMUNOL SECT,TOKYO 108,JAPAN
[4] MITA INST,TOKYO,JAPAN
来源：
VOX SANGUINIS | 1992年 / 63卷 / 02期
关键词：
D O I：
10.1111/j.1423-0410.1992.tb02495.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Hepatitis B virus (HBV) DNA was tested for in 294 blood units which had antibody against hepatitis B core antigen (anti-HBc) as the isolated serological marker of HBV infection. After amplification by polymerase chain reaction, HBV DNA was detected in 12 (6.9%) of 175 units that were positive for anti-HBc with hemagglutination inhibition titers greater-than-or-equal-to 2(6), significantly more often than in none of 119 units with titers less-than-or-equal-to 2(5) (p < 0.01). These results indicate that the exclusion of blood units with isolated high-titer anti-HBc would be effective for further decreasing the risk of posttransfusion hepatitis B.
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页码：107 / 111
页数：5
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