REGULATION OF EXTRACELLULAR-MATRIX DEGRADATION BY CELL EXTRACELLULAR-MATRIX INTERACTIONS

被引：52

作者：

WERB, Z

TREMBLE, P

DAMSKY, CH

机构：

[1] UNIV CALIF SAN FRANCISCO,RADIOBIOL & ENVIRONM HLTH LAB,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT ANAT,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,DEPT PHARMACOL,SAN FRANCISCO,CA 94143

[4] UNIV CALIF SAN FRANCISCO,DEPT STOMATOL,SAN FRANCISCO,CA 94143

来源：

CELL DIFFERENTIATION AND DEVELOPMENT | 1990年 / 32卷 / 03期

关键词：

CYTOSKELETON; FIBRONECTIN RECEPTOR; INTEGRIN; METALLOPROTEINASE; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASES;

D O I：

10.1016/0922-3371(90)90043-V

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

An appropriate balance of extracellular matrix synthesis and degradation is required for normal morphogenesis and maintenance of tissue architecture. Extracellular matrix molecules and their receptors, as well as proteinase and their inhibitors, are all involved in matrix remodeling. In this report we show that signal transduction through extracellular matrix receptors regulates matrix remodeling.

引用

页码：299 / 306

页数：8

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