EFFECTS OF SENNOSIDES ON CELLULAR ELECTRIC-ACTIVITIES IN SMOOTH-MUSCLE CELLS OF GUINEA-PIG TAENIA-COLI

被引：0
作者：
YANG, WX
JIN, ZG
XU, WS
TIAN, ZS
GUO, SD
机构：
来源：
ACTA PHARMACOLOGICA SINICA | 1993年 / 14卷 / 05期
关键词：
RHUBARB; POLYSACCHARIDES; COLON; SMOOTH MUSCLE; MICROELECTRODES; ELECTROPHYSIOLOGY;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The effects of sennosides (Sen, an extract of Chinese rhubarb) on cellular spontaneous electric activities of guinea pig taenia coli were studied by intracellular microelectrode technique. Sen 0.1-20 mmol . L-1 improved the depolarization of cell membrane, quickened the burst of slow wave potential, and increased notably the frequency of spike potentials. Sen (20 mmol.L-1) induced spontaneous spike potentials. These results provide direct evidence for the enhancing effect of Sen on intestinal peristalsis at cellular level.
引用
收藏
页码：430 / 432
页数：3
相关论文
共 6 条
  • [1] BULBRING E, 1954, J PHYSIOL-LONDON, V125, P302
  • [2] EFFECTS OF SENNOSIDES ON COLONIC MYOELECTRICAL ACTIVITY IN MAN
    FREXINOS, J
    STAUMONT, G
    FIORAMONTI, J
    BUENO, L
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1989, 34 (02) : 214 - 219
  • [3] JIAO DH, 1982, CHIN J INTEGR MED, V2, P85
  • [4] JIN BL, 1989, CHIN J CHIN MATERIA, V14, P47
  • [5] JIN ZG, 1992, ACTA SCI NATUR U NAN, V1, P70
  • [6] TAKEMI T, 1985, HERBAL MED KAMPO PAS, P41
1