THE EFFECT OF DILTIAZEM ON THE CARDIOVASCULAR-RESPONSE TO TRACHEAL INTUBATION

被引：37

作者：

MIKAWA, K ^{[1
]}

IKEGAKI, J ^{[1
]}

MAEKAWA, N ^{[1
]}

GOTO, R ^{[1
]}

KAETSU, H ^{[1
]}

OBARA, H ^{[1
]}

机构：

[1] HYOGO MED CTR ADULTS,DEPT ANAESTHESIOL,AKASHI 673,JAPAN

来源：

ANAESTHESIA | 1990年 / 45卷 / 04期

关键词：

diltiazem; Intubation; tracheal; Pharamcology;

D O I：

10.1111/j.1365-2044.1990.tb14734.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The efficacy of diltiazem in the attenuation of the cardiovascular response to laryngoscopy and tracheal intubation was studied in patients who received 0.2 or 0.3 mg/kg diltiazem 60 seconds before the start of laryngoscopy. These data were compared with a control group who received saline. Each group consisted of 10 patients who had elective surgery. Patients who received saline showed a significant increase in mean arterial pressure and rate pressure product associated with tracheal intubation. These increases after tracheal intubation were reduced in diltiazem‐treated patients compared with those of the control group (p < 0.05). The data suggest that a bolus injection of diltiazem is a simple, practical and effective method to attenuate the hypertensive response to laryngoscopy and tracheal intubation. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：289 / 293

页数：5

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