THE INFLUENCE OF PRECULTURE ON THE PROCESS PERFORMANCE OF PENICILLIN-V PRODUCTION IN A 100-1 AIRLIFT TOWER LOOP REACTOR

被引：0

作者：

MOLLER, J ^{[1
]}

NIEHOFF, J ^{[1
]}

HOTOP, S ^{[1
]}

DORS, M ^{[1
]}

SCHUGERL, K ^{[1
]}

机构：

[1] UNIV HANOVER,INST TECH CHEM,CALLINSTR 3,W-3000 HANNOVER,GERMANY

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 1992年 / 37卷 / 02期

关键词：

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The influence of stirrer speed in the third preculture on the performance of penicillin V production by Penicillium chrysogenum in complex medium in a 100-l air-lift tower loop reactor was investigated. The process performance in the main culture was improved by increasing the stirrer speed from 500 to 750 rpm: the pellet size was reduced to half, the cell growth was influenced only slightly, but the production phase was extended considerably, and the final penicillin concentration was increased from 5.1 g l-1 to 10.4 g l-1.

引用

页码：157 / 163

页数：7

共 16 条

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