MOLECULAR APPROACHES TO THE SEGMENTATION OF THE HINDBRAIN

被引：112

作者：

WILKINSON, DG

KRUMLAUF, R

机构：

[1] Laboratory of Eukaryotic Molecular Genetics, National Institute for Medical Research, The Ridgeway, London, NW7 1AA, Mill Hill

来源：

TRENDS IN NEUROSCIENCES | 1990年 / 13卷 / 08期

关键词：

D O I：

10.1016/0166-2236(90)90145-Z

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent studies have shown that the rhombomeric bulges of the developing vertebrate hindbrain reflect segmental mechanisms that generate pattern in this region of the CNS. Although little is known of the genetic basis of this segmentation, in situ hybridization studies have provided circumstantial evidence that certain 'zinc-finger' and homeobox genes have roles in the development of segments in the early mouse hindbrain. We discuss the implications of these findings for the function of these genes in hindbrain development. © 1990.

引用

页码：335 / 339

页数：5

共 39 条

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