INFECTION AND REACTIVATION WITH CYTOMEGALOVIRUS STRAINS IN LUNG-TRANSPLANT RECIPIENTS

被引：22
|
作者：
SMYTH, RL
SINCLAIR, J
SCOTT, JP
GRAY, JJ
HIGENBOTTAM, TW
WREGHITT, TG
WALLWORK, J
BORYSIEWICZ, LK
机构：
[1] UNIV CAMBRIDGE,ADDENBROOKES HOSP,DEPT MED,CAMBRIDGE CB2 2QQ,ENGLAND
[2] ADDENBROOKES HOSP,PUBL HLTH LAB,CAMBRIDGE CB2 2QQ,ENGLAND
[3] PAPWORTH HOSP,HEART LUNG TRANSPLANT UNIT,CAMBRIDGE CB3 8RE,ENGLAND
来源：
TRANSPLANTATION | 1991年 / 52卷 / 03期
基金：
英国惠康基金;
关键词：
D O I：
10.1097/00007890-199109000-00017
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Cytomegalovirus pneumonia is a major cause of morbidity and death following lung transplantation (LT)* (1). The case fatality rate is highest in the CMV-seronegative recipients (R-) of organs from seropositive donors (D+), which suggests that transmission of CMV may occur with the graft (1), but in seropositive recipients (R+) the comparative importance of reactivation of endogenous virus and reinfection with donor virus is poorly understood.
引用
收藏
页码：480 / 481
页数：2
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