PHARMACOLOGICAL DRUGS FOR CONTROLLED HYPOTENSION

被引:32
作者
TESTA, LD [1 ]
TOBIAS, JD [1 ]
机构
[1] VANDERBILT UNIV,DEPT PEDIAT,DIV PEDIAT ANESTHESIOL CRIT CARE MED,NASHVILLE,TN 37232
关键词
ADENOSINE DIPHOSPHATE; MONOPHOSPHATE; TRIPHOSPHATE; ALPHA-ADRENERGIC ANTAGONISTS; ANESTHETICS; INHALATION; BETA-ADRENERGIC ANTAGONISTS; BLOOD LOSS; SURGICAL; CALCIUM CHANNEL BLOCKERS; CLONIDINE; DILTIAZEM; ENFLURANE; ESMOLOL; HALOTHANE; HYPOTENSION; CONTROLLED; ISOFLURANE; LABETALOL; NICARDIPINE; NIFEDIPINE; NITROGLYCERIN; NITROPRUSSIDE; PROSTAGLANDIN E; TRIMETHAPHAN; VASODILATORS; DIRECT-ACTING; VERAPAMIL;
D O I
10.1016/0952-8180(95)00010-F
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Due to the risks of transfusion reactions and the transmission of infectious diseases, there has been increased interest in measures to limit intraoperative blood loss and avoid the need for homologous transfusion. Controlled hypotension is one technique that has been used to limit intraoperative blood loss. Several drugs have been used alone or in combination for controlled hypotension, including the inhalational anesthetics, direct acting vasodilators such as nitroglycerin and nitroprusside, beta adrenergic antagonists, and calcium channel blockers. Various drugs available to the clinician for controlled hypotension are reviewed.
引用
收藏
页码:326 / 337
页数:12
相关论文
共 64 条
[1]  
Gardner, The control of bleeding during operation by induced hypotension, JAMA, 132, pp. 572-576, (1946)
[2]  
Gilles, Anaesthetic factors in the causation and prevention of excessive bleeding during surgical operations, Ann R Coll Surg Eng, pp. 204-221, (1950)
[3]  
Eckenhoff, Rich, Clinical experiences with deliberate hypotension, Anesth Analg, 45, pp. 21-88, (1966)
[4]  
Sollevi, Hypotensive anesthesia and blood loss, Acta Anaesthesiologica Scandinavica, 89, pp. 39-43, (1988)
[5]  
Sivarajan, Amory, Everett, Buffington, Blood pressure, not cardiac output, determines blood loss during induced hypotension, Anesth Analg, 59, pp. 203-206, (1980)
[6]  
Macnab, Manninen, Lam, Gelb, The stress response to induced hypotension for cerebral aneurysm surgery. a comparison of two hypotensive techniques, Can J Anaesth, 35, pp. 111-115, (1988)
[7]  
Michenfelder, Sundt, Fode, Sharbrough, Isoflurane when compared to enflurane and halothane decreases the frequency of cerebral ischemia during carotid endarterectomy, Anesthesiology, 67, pp. 336-340, (1987)
[8]  
Newman, Gelb, Lam, The effect of isofluraneinduced hypotension on cerebral blood flow and cerebral metabolic rate for oxygen in humans, Anesthesiology, 64, pp. 307-310, (1987)
[9]  
Haraldsted, Asmussen, Herlevsen, Cold, Cerebral arteriovenous difference of oxygen during gradual and sudden increase of the concentration of isoflurane for induction of deliberate hypotension, Acta Anaesthesiol Scand, 36, pp. 142-144, (1992)
[10]  
Madsen, Cold, Hansen, Bardrum, Kruse-Larsen, Cerebral blood flow and metabolism during isofluraneinduced hypotension in patients subjected to surgery for cerebral aneurysms, Br J Anaesth, 59, pp. 1204-1207, (1987)