SECRETIN-LIKE BIOACTIVITY IN EXTRACTS OF PORCINE BRAIN

被引：84
作者：
MUTT, V
CARLQUIST, M
TATEMOTO, K
机构：
来源：
LIFE SCIENCES | 1979年 / 25卷 / 20期
关键词：
D O I：
10.1016/0024-3205(79)90472-7
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Porcine brain extracts were found to stimulate exocrine pancreatic secretion in a secretin-like fashion. The active material may be secretin since it behaved as secretin through several purification steps including chromatography on Sephadex G-25 and carboxymethyl cellulose, and on high performance liquid chromatography. Furthermore, the highly purified preparation contained, like secretin, C-terminal valine amide, and one of its tryptic fragments had the same mobility as the C-terminal tryptic fragment of secretin on thin layer chromatography. © 1979.
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页码：1703 / 1707
页数：5
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