PREPARATION AND ANTI-DIABETIC ACTIVITY OF SOME SULFONYLUREA DERIVATIVES OF 3,5-DISUBSTITUTED PYRAZOLES

被引：67

作者：

SOLIMAN, R

机构：

[1] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Alexandria

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1979年 / 22卷 / 03期

关键词：

D O I：

10.1021/jm00189a022

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four series of p-[3, 5-dimethyl-(and 5-methyl-3-carboxy-) pyrazole-1]benzenesulfonylureas, thioureas, 2-thiohydantions, and 5, 6-dihydro-4(3H)-oxo-2(1H)-pyrimidinethiones were prepared for evaluation as hypoglycemic agents. Biological testing of these compounds showed that some possessed antidiabetic activity. © 1979, American Chemical Society. All rights reserved.

引用

页码：321 / 325

页数：5

共 16 条

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