MECHANISM OF ANTIINFLAMMATORY AND ANTITHERMAL BURN ACTION OF CPASE FROM ALOE-ARBORESCENS MILLER VAR NATALENSIS BERGER IN RATS AND MICE

被引：19
作者：
OBATA, M
ITO, S
BEPPU, H
FUJITA, K
NAGATSU, T
机构：
[1] FUJITA HLTH UNIV, SCH MED, INST PHARMACOGNOSY, 1865 ISSHIKI, HISAI, MIE 51412, JAPAN
[2] FUJITA HLTH UNIV, SCH MED, INST COMPREHENS MED SCI, TOYOAKE, AICHI 47011, JAPAN
来源：
PHYTOTHERAPY RESEARCH | 1993年 / 7卷
关键词：
ALOE; ANTIINFLAMMATORY ACTION; ANTITHERMAL BURN ACTION; CARBOXYPEPTIDASE; BRADYKININ; VASCULAR PERMEABILITY;
D O I：
10.1002/ptr.2650070711
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Carboxypeptidase (CPase) was partially purified from Kidachi aloe (Aloe arborescens Miller var. natalensis Berger) by an FPLC system, and was administered intravenously to female ICR mice with inflammation. The enzyme preparation exhibited significant analgesic effects and inhibited vascular permeability in the abdominal region. It also revealed an antithermal burn action on the hind paw, when it was administered to female Wistar rats intravenously.
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页码：S30 / S33
页数：4
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