AN INTEGRATED MULTIELECTRODE ELECTROPHYSIOLOGY SYSTEM

被引:14
作者
BORRONI, A [1 ]
CHEN, FM [1 ]
LECURSI, N [1 ]
GROVER, LM [1 ]
TEYLER, TJ [1 ]
机构
[1] NORTHEASTERN OHIO UNIV,COLL MED,DEPT NEUROBIOL,ROOTSTOWN,OH 44272
关键词
ELECTROPHYSIOLOGY SOFTWARE; MULTICHANNEL AMPLIFIER; MULTI-LEAD ELECTRODE; CURRENT SOURCE DENSITY ANALYSIS;
D O I
10.1016/0165-0270(91)90043-Y
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
An integrated system for recording and analyzing electrophysiological data from multiple channels is described. The system uses an MS-DOS microcomputer, a 16-channel amplifier, and multiple-tipped electrode arrays designed for use in intact and slice preparations. The system is designed for applications where the collection and analysis of multiple-channel electrophysiological data is desirable, including the construction of current source density (CSD) profiles from field potential data. The software incorporates on-line averaging, CSD and freeze-frame capabilities to guide the experiment in progress. Additional off-line analyses include multiple unit activity, power spectra, and automatic scans of data files for peak amplitude, area, latency, and slope within user-defined latency windows. All data and analyses can be exported to commercial statistical/graphical programs for the creation of publication-ready figures.
引用
收藏
页码:177 / 184
页数:8
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