LORAZEPAM DISCONTINUATION PROMOTES INVERSE AGONIST EFFECTS OF BENZODIAZEPINES

被引：23
作者：
SCHATZKI, A
LOPEZ, F
GREENBLATT, DJ
SHADER, RI
MILLER, LG
机构：
[1] TUFTS UNIV,SCH MED,DEPT PSYCHIAT,DIV CLIN PHARMACOL,BOSTON,MA 02111
[2] TUFTS UNIV,SCH MED,DEPT MED & PHARMACOL,DIV CLIN PHARMACOL,BOSTON,MA 02111
[3] NEW ENGLAND MED CTR,BOSTON,MA 02111
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 1989年 / 98卷 / 02期
关键词：
D O I：
10.1111/j.1476-5381.1989.tb12617.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：451 / 454
页数：4
相关论文
共 23 条
[1]   CHRONIC CLONAZEPAM ADMINISTRATION INDUCES BENZODIAZEPINE RECEPTOR SUBSENSITIVITY [J].
CRAWLEY, JN ;
MARANGOS, PJ ;
STIVERS, J ;
GOODWIN, FK .
NEUROPHARMACOLOGY, 1982, 21 (01) :85-89
[2]   RECOVERY FROM LORAZEPAM TOLERANCE AND THE EFFECTS OF A BENZODIAZEPINE ANTAGONIST (RO-15-1788) ON THE DEVELOPMENT OF TOLERANCE [J].
FILE, SE .
PSYCHOPHARMACOLOGY, 1982, 77 (03) :284-288
[3]   ANALYSIS OF LORAZEPAM AND ITS GLUCURONIDE METABOLITE BY ELECTRON-CAPTURE GAS-LIQUID-CHROMATOGRAPHY - USE IN PHARMACOKINETIC STUDIES OF LORAZEPAM [J].
GREENBLATT, DJ ;
FRANKE, K ;
SHADER, RI .
JOURNAL OF CHROMATOGRAPHY, 1978, 146 (02) :311-320
[4]  
GREENBLATT DJ, 1983, NEW ENGL J MED, V309, P410
[5]   DEPENDENCE, TOLERANCE, AND ADDICTION TO BENZODIAZEPINES - CLINICAL AND PHARMACOKINETIC CONSIDERATIONS [J].
GREENBLATT, DJ ;
SHADER, RI .
DRUG METABOLISM REVIEWS, 1978, 8 (01) :13-28
[6]  
Haefely W. E., 1985, ADV DRUG RES, V14, P165
[7]  
LITTLE H J, 1986, British Journal of Pharmacology, V89, p796P
[8]  
Little H J, 1987, J Psychopharmacol, V1, P35, DOI 10.1177/026988118700100108
[9]  
LITTLE H J, 1984, British Journal of Pharmacology, V83, p360P
[10]  
LITTLE HJ, 1987, BRAIN RES BULL, V19, P371
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