EFFECT OF LIPID-PEROXIDATION ON BEATING FREQUENCY OF HUMAN SPERM TAIL

被引:0
作者
HONG, CY
LEE, MF
LAI, LJ
WANG, CP
机构
[1] NATL YANG MING MED COLL,INST TRADIT MED,TAIPEI 11221,TAIWAN
[2] NATL YANG MING MED COLL,INST CLIN MED,TAIPEI 11221,TAIWAN
关键词
LIPID PEROXIDATION; SPERM MOTILITY; ALBUMIN; GLUTATHIONE; HUMAN;
D O I
暂无
中图分类号
R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
摘要
The tail beat frequency (TBF) of sperm was measured with a sperm-head fixation method which was based on the tendency of sperm to attach its head to the surface of a glass slide. Ferrous sulphate, a promotor of lipid peroxidation, inhibited TBF within 5 min of mixing with sperm. This inhibition can be reversed dose-dependently by superoxide dismutase, catalase, glutathione, and albumin. It was concluded that TBF could be a new pharmacological model for studying the effect of lipid peroxidation and antioxidant on sperm motility. Both enzymatic and nonenzymatic antioxidants can be screened with this method.
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页码:61 / 65
页数:5
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