Vitamin D and multiple sclerosis

被引:0
|
作者
Harandi, Asghar Amini [1 ]
Harandi, Ali Amini [2 ]
Pakdaman, Hossein [2 ]
Sahraian, Mohammad Ali [3 ]
机构
[1] Jahrom Univ Med Sci, Sch Med, Dept Biochem, Jahrom, Iran
[2] Shahid Beheshti Univ Med Sci, Sch Med, Dept Neurol, Tehran, Iran
[3] Univ Tehran Med Sci, Neurosci Inst, MS Res Ctr, Tehran, Iran
关键词
Multiple Sclerosis; Vitamin D; Vitamin D Receptor; Polymorphism;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. The main pathogenesis of MS has long been thought to be an immune mediated disorder of the central nervous system. The function of the immune system is under the influence of vitamin D which as a modulator of immune response could play a role in autoimmune diseases including MS. Deficiency of vitamin D or variations in DNA sequence (polymorphism) of vitamin D receptor gene diminishes its optimal function on immune system that consequently could lead to increasing risk of MS. However, its role in development and modulating the course of MS is still under investigation. In this review we aimed to discuss the role of vitamin D in body, immune system and consequently altering the risk of MS.
引用
收藏
页码:1 / 6
页数:6
相关论文
共 50 条
  • [1] Vitamin D and remyelination in multiple sclerosis
    Matias-Guiu, J.
    Oreja-Guevara, C.
    Matias-Guiu, J. A.
    Gomez-Pinedo, U.
    NEUROLOGIA, 2018, 33 (03): : 177 - 186
  • [2] Multiple Sclerosis and Vitamin D
    Bello, Carlos Tavares
    REVISTA PORTUGUESA DE ENDOCRINOLOGIA DIABETES E METABOLISMO, 2023, 18 : 68 - 70
  • [3] Vitamin D and multiple sclerosis
    Pozuelo-Moyano, Beatriz
    Benito-Leon, Julian
    REVISTA DE NEUROLOGIA, 2013, 56 (04) : 243 - 251
  • [4] Vitamin D and Multiple Sclerosis
    Weinstock-Guttman, Bianca
    Mehta, Bijal K.
    Ramanathan, Murali
    Karmon, Yuval
    Henson, Lily Jung
    Halper, June
    Riskind, Peter
    NEUROLOGIST, 2012, 18 (04) : 179 - 183
  • [5] Vitamin D and multiple sclerosis
    Raghuwanshi, Anita
    Joshi, Sneha S.
    Christakes, Sylvia
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 105 (02) : 338 - 343
  • [6] Therapeutic potential of vitamin D for multiple sclerosis
    Niino, Masaaki
    Fukazawa, Toshiyuki
    Kikuchi, Seiji
    Sasaki, Hidenao
    CURRENT MEDICINAL CHEMISTRY, 2008, 15 (05) : 499 - 505
  • [7] Vitamin D and multiple sclerosis
    Hewer, Sarah
    Lucas, Robyn
    van der Mei, Ingrid
    Taylor, Bruce V.
    JOURNAL OF CLINICAL NEUROSCIENCE, 2013, 20 (05) : 634 - 641
  • [8] The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis
    Smolders, Joost
    Peelen, Evelyn
    Thewissen, Marielle
    Menheere, Paul
    Tervaert, Jan Willem Cohen
    Hupperts, Raymond
    Damoiseaux, Jan
    AUTOIMMUNITY REVIEWS, 2009, 8 (07) : 621 - 626
  • [9] What is the Real Fate of Vitamin D in Multiple Sclerosis?
    Shaygannejad, Vahid
    Tolou-Ghamari, Zahra
    INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 2013, 4 : S159 - S164
  • [10] Vitamin D treatment in multiple sclerosis
    Myhr, Kjell-Morten
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 286 (1-2) : 104 - 108