4-(3-Fluoroanilino) thieno[2,3-b] pyridine6-carboxylic acid

被引：1

作者：

Pinheiro, Luiz C. S. ^{[1
]}

Bernardino, Alice M. R. ^{[2
]}

Wardell, Solange M. S. V. ^{[3
]}

Wardell, James L. ^{[4
]}

Tiekink, Edward R. T. ^{[5
]}

机构：

[1] Fundacao Oswaldo Cruz, Inst Tecnol Farmacos, Dept Sibtese Organ, BR-21041250 Rio De Janeiro, RJ, Brazil

[2] Univ Fed Fluminense, Inst Quim, Dept Quim Organ, BR-24210150 Niteroi, RJ, Brazil

[3] CHEMSOL, Aberdeen AB15 5NY, Scotland

[4] Fundacao Oswaldo Cruz FIOCRUZ, CDTS, BR-21040900 Rio De Janeiro, RJ, Brazil

[5] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2012年 / 68卷

关键词：

D O I：

10.1107/S1600536812027195

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C14H9FN2O2S, the thieno[2,3-b] pyridine residue is almost planar (r.m.s. deviation = 0.0194 angstrom), with the carboxylic acid group [dihedral angle = 11.9 (3)(circle)] and the benzene ring [71.1 (4)(circle)] being twisted out of this plane to different extents. An intramolecular N-H...O(carbonyl) hydrogen bond closes an S(6) ring. Supramolecular chains along [011] mediated by O-H...N(pyridine) hydrogen bonds feature in the crystal. A three-dimensional architecture is completed by pi-pi interactions occurring between the benzene ring and the two rings of the thieno[2,3-b] pyridine residue [centroid-centroid distances = 3.6963 (13) and 3.3812 (13) angstrom]. The F atom is disordered over the two meta sites in a near statistical ratio [0.545 (5): 0.455 (5)].

引用

页码：O2217 / +

页数：10

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