ABSENCE OF HTLV-I AND HTLV-II PROVIRAL GENOME IN THE BRAINS OF PATIENTS WITH MULTIPLE-SCLEROSIS AND AMYOTROPHIC-LATERAL-SCLEROSIS

被引:4
作者
DEKABAN, GA [1 ]
HUDSON, AJ [1 ]
RICE, GPA [1 ]
机构
[1] UNIV WESTERN ONTARIO,DEPT CLIN NEUROL SCI,LONDON N6A 5A5,ONTARIO,CANADA
关键词
D O I
10.1017/S0317167100041640
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Previous studies have failed to provide serological evidence to incriminate a retroviral infection in the cause of multiple sclerosis. Gene amplification techniques have also tailed to identify retroviral footprints in DNA from peripheral blood leukocytes. Here we provide evidence that proviral DNA of HTLV-I and HTLV-II is not found in the central nervous system tissues of patients with multiple sclerosis, patients with amyotrophic lateral sclerosis and controls.
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页码:458 / 461
页数:4
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