CIPROFLOXACIN FOR TREATMENT OF SEVERE TYPHOID-FEVER IN CHILDREN

被引：56

作者：

DUTTA, P ^{[1
]}

RASAILY, R ^{[1
]}

SAHA, MR ^{[1
]}

MITRA, U ^{[1
]}

BHATTACHARYA, SK ^{[1
]}

BHATTACHARYA, MK ^{[1
]}

LAHIRI, M ^{[1
]}

机构：

[1] DR B C ROY MEM HOSP CHILDREN,CALCUTTA 700054,INDIA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 05期

关键词：

D O I：

10.1128/AAC.37.5.1197

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Eighteen children with bacteriologically confirmed severe typhoid fever were initially treated intravenously with ciprofloxacin (10 mg/kg of body weight per day). Clinical cure with eradication of multiresistant Salmonella typhi infection was observed in 17 patients (94.4%; 95% confidence interval [CI], 84 to 100%). Children regained normal consciousness within an average of 2 days (95% CI, 1.8 to 2.2 days). The temperatures of the children returned to normal within 3.3 days (95% CI, 3.1 to 3.5 days). Complications were not observed during the hospital stay or a 3-month follow-up period. Relapse and carrier state were also not encountered during the follow-up period.

引用

页码：1197 / 1199

页数：3

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