HEMATOPOIETIN SUBFAMILY CLASSIFICATION BASED ON SIZE, GENE ORGANIZATION AND SEQUENCE HOMOLOGY

被引:58
作者
BOULAY, JL [1 ]
PAUL, WE [1 ]
机构
[1] NIAID,IMMUNOL LAB,BETHESDA,MD 20892
关键词
D O I
10.1016/0960-9822(93)90002-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The hematopoietins constitute a family of structurally related proteins that includes many cytokines, growth factors and hormones. We propose a classification for hematopoietins based on their size, gene organization and sequences; in addition, we further suggest that three cytokines, IL-11, IL-12 α chain and IL-13, are hematopoietins, and we place them in specific subgroups. © 1993.
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页码:573 / 581
页数:9
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