ALPHA-ADRENERGIC AND BETA-ADRENERGIC RECEPTORS IN HYPERTENSION

被引：0
|
作者：
MULLER, K
机构：
来源：
NIEREN-UND HOCHDRUCKKRANKHEITEN | 1992年 / 21卷 / 11期
关键词：
HYPERTENSION; CARDIAC OUTPUT; PERIPHERAL RESISTANCE; ALPHA-ADRENERGIC; BETA-ADRENERGIC RECEPTOR; ANGIOTENSIN-II; MYOGENIC REACTIVITY; DIFFERENTIAL THERAPY;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Long-term studies on hemodynamics of untreated hypertensives have shown that an initial high cardiac output usually disappears over a 5- to 10 year period and the total peripheral resistance increases instead. Alpha- and beta-adrenergic receptors seem to play an important role as cause of these changes in hemodynamics. Angiotensin II and the myogenetic reactivity can cause an enhancement of the peripheral resistance which is already increased by an alpha-adrenergic activity. Based on this findings, it is possible to develope a differential therapy with blocker, alpha-blocker, ACE-inhibitor and Ca-antagonist.
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页码：698 / 700
页数：3
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