EXPRESSION OF TRANSFORMING GROWTH FACTOR-BETA-1 IN THE SUBMANDIBULAR-GLAND OF THE RAT

被引：27
作者：
AMANO, O [1 ]
TSUJI, T [1 ]
NAKAMURA, T [1 ]
ISEKI, S [1 ]
机构：
[1] KYUSHU UNIV,FAC SCI,DEPT BIOL,FUKUOKA 812,JAPAN
来源：
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY | 1991年 / 39卷 / 12期
关键词：
TRANSFORMING GROWTH FACTOR-BETA-1; IMMUNOCYTOCHEMISTRY; INSITU HYBRIDIZATION; SUBMANDIBULAR GLAND; RAT;
D O I：
10.1177/39.12.1940322
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
We employed immunocytochemical and in situ hybridization techniques to study the expression of transforming growth factor beta-1 (TGF-beta-1) in rat submandibular gland. Immunoreactivity for TGF-beta-1 was observed in the cells of granular convoluted tubules (GCTs), striated ducts, and excretory ducts, whereas it was absent in the intercalated ducts and secretory acini in both male and female rats. Immunoelectron microscopy revealed the ultrastructural localization of TGF-beta-1 in the secretory granules of GCT cells. On the other hand, signals for rat TGF-beta-1 mRNA were abundant in the GCT and striated duct cells but were lacking in the excretory duct cells. These results provided evidence for the production of TGF-beta-1 in the GCTs and striated ducts of rat submandibular gland.
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收藏
页码：1707 / 1711
页数：5
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