OBSERVATION OF ENZYME BOUND INTERMEDIATES IN THE BIOSYNTHESIS OF PREUROPORPHYRINOGEN BY PBG DEAMINASE

被引：18

作者：

APLIN, RT

BALDWIN, JE

PICHON, C

ROESSNER, CA

SCOTT, AI

SCHOFIELD, CJ

STOLOWICH, NJ

WARREN, MJ

机构：

[1] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

[2] TEXAS A&M UNIV SYST,DEPT CHEM,CTR BIOL NMR,COLLEGE STN,TX 77843

[3] UNIV LONDON,QUEEN MARY & WESTFIELD COLL,LONDON E1 4NS,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 10期

关键词：

D O I：

10.1016/S0960-894X(01)80453-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Electrospray mass spectrometry was used to observe covalently bound enzyme-intermediate complexes during the catalytic assembly of the linear tetrapyrrole, preuroporphyrinogen, by the enzyme porphobilinogen deaminase.

引用

页码：503 / 506

页数：4

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