HUMAN CHORIONIC-GONADOTROPIN AND ALPHA-FETOPROTEIN LEVELS IN MATCHED SAMPLES OF AMNIOTIC-FLUID, EXTRAEMBRYONIC CELOMIC FLUID, AND MATERNAL SERUM IN THE 1ST TRIMESTER OF PREGNANCY

被引：45

作者：

WATHEN, NC ^{[1
]}

CASS, PL ^{[1
]}

KITAU, MJ ^{[1
]}

CHARD, T ^{[1
]}

机构：

[1] HOMERTON HOSP,LONDON EC1A 7BE,ENGLAND

来源：

PRENATAL DIAGNOSIS | 1991年 / 11卷 / 03期

关键词：

HUMAN CHORIONIC GONADOTROPIN; ALPHA-FETOPROTEIN; AMNIOTIC FLUID; EXTRAEMBRYONIC COELOM; 1ST-TRIMESTER AMNIOCENTESIS;

D O I：

10.1002/pd.1970110303

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Separately identified samples of amniotic fluid and extraembryonic coelomic fluid obtained by high resolution transvaginal ultrasound-guided amniocentesis from 32 women between 7 and 12 weeks of pregnancy were analysed for human chorionic gonadotrophin (hCG) and alpha-fetoprotein (AFP). There was a highly significant difference between the hCG levels in amniotic fluid (median level 6.3 U/ml; range 1.6-310.0 U/ml) and those in extraembryonic coelomic fluid (median level 400.0 U/ml; range 135.0-2250.0 U/ml) (p < 0.001; Mann-Whitney U-test). The levels of AFP were very similar in amniotic fluid (median 26.0 kU/ml; range 10.0-116.5 kU/ml) and extraembryonic coelomic fluid (median level 24.1 kU/ml; range 12.4-94.4 kU/ml).

引用

页码：145 / 151

页数：7

共 11 条

[1]

BRAMBATI B, 1991, IN PRESS ULTRASOUND

[2] 1ST-TRIMESTER MATERNAL SERUM BIOCHEMICAL INDICATORS IN DOWN SYNDROME [J].