AMINO-ACID-SEQUENCE ELUCIDATION OF HUMAN ACROSIN-TRYPSIN INHIBITOR (HUSI-II) REVEALS THAT KAZAL-TYPE PROTEINASE-INHIBITORS ARE STRUCTURALLY RELATED TO BETA-SUBUNITS OF GLYCOPROTEIN HORMONES

被引：30

作者：

FINK, E ^{[1
]}

HEHLEINFINK, C ^{[1
]}

EULITZ, M ^{[1
]}

机构：

[1] GESELL STRAHLEN & UMWELTFORSCH MBH,INST CLIN MOLEC BIOL,W-8000 MUNICH 70,GERMANY

来源：

FEBS LETTERS | 1990年 / 270卷 / 1-2期

关键词：

Acrosin-trypsin inhibitor (human seminal plasma); Chorionic gonadotropin; Glycoprotein hormone β-subunit; Kazal-type inhibitor; Luteinizing hormone;

D O I：

10.1016/0014-5793(90)81273-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The amino acid sequence of the acrosin-trypsin inhibitor HUSI-II from human seminal plasma is presented which unequivocally identifies HUSI-II as being of Kazal-type. In addition, the HUSI-II sequence shows a striking similarity to the middle part of glycoprotein hormone β-subunits thus revealing a hitherto unknown structural and evolutionary relationship between Kazal-type inhibitors and glycoprotein hormones. © 1990.

引用

页码：222 / 224

页数：3

共 24 条

[1] PRIMARY STRUCTURE OF HUMAN PANCREATIC SECRETORY TRYPSIN-INHIBITOR - AMINO-ACID SEQUENCE OF REDUCED S-AMINOETHYLATED PROTEIN [J].

BARTELT, DC ;

SHAPANKA, R ;

GREENE, LJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1977, 179 (01) :189-199

[2]

BARTELT DC, 1971, J BIOL CHEM, V246, P2218

[3] 3-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN PANCREATIC SECRETORY TRYPSIN-INHIBITOR (KAZAL TYPE) AND TRYPSINOGEN AT 1-8 A RESOLUTION - STRUCTURE SOLUTION, CRYSTALLOGRAPHIC REFINEMENT AND PRELIMINARY STRUCTURAL INTERPRETATION [J].

BOLOGNESI, M ;

GATTI, G ;

MENEGATTI, E ;

GUARNERI, M ;

MARQUART, M ;

PAPAMOKOS, E ;

HUBER, R .

JOURNAL OF MOLECULAR BIOLOGY, 1982, 162 (04) :839-868

[4]

FINK E, 1971, H-S Z PHYSIOL CHEM, V352, P1591

[5]

FINK E, 1973, PROTIDES BIOL FLUIDS, V20, P425

[6]

FRITZ H, 1988, BIOL CHEM H-S, V369, P79

[7]

GREENE LJ, 1969, J BIOL CHEM, V244, P2646

[8]

HAENDLE H, 1965, H-S Z PHYSIOL CHEM, V343, P185

[9] CHICKEN OVOMUCOID - DETERMINATION OF ITS AMINO-ACID-SEQUENCE, DETERMINATION OF THE TRYPSIN REACTIVE SITE, AND PREPARATION OF ALL 3 OF ITS DOMAINS [J].

KATO, I ;

SCHRODE, J ;

KOHR, WJ ;

LASKOWSKI, M .

BIOCHEMISTRY, 1987, 26 (01) :193-201

[10] ISOLATION OF A CRYSTALLINE TRYPSIN INHIBITOR-ANTICOAGULANT PROTEIN FROM PANCREAS [J].

KAZAL, LA ;

SPICER, DS ;

BRAHINSKY, RA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1948, 70 (09) :3034-3040

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