HIV WITH REDUCED SENSITIVITY TO ZIDOVUDINE (AZT) ISOLATED DURING PROLONGED THERAPY

被引：1575
作者：
LARDER, BA
DARBY, G
RICHMAN, DD
机构：
[1] UNIV CALIF SAN DIEGO,DEPT PATHOL,SAN DIEGO,CA 92103
[2] UNIV CALIF SAN DIEGO,DEPT MED,SAN DIEGO,CA 92103
[3] VET ADM MED CTR,SAN DIEGO,CA 92161
来源：
SCIENCE | 1989年 / 243卷 / 4899期
关键词：
D O I：
10.1126/science.2467383
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1731 / 1734
页数：4
相关论文
共 22 条
  • [1] BURNS WH, 1982, LANCET, V1, P421
  • [2] DEVELOPMENT OF A SENSITIVE QUANTITATIVE FOCAL ASSAY FOR HUMAN IMMUNODEFICIENCY VIRUS INFECTIVITY
    CHESEBRO, B
    WEHRLY, K
    [J]. JOURNAL OF VIROLOGY, 1988, 62 (10) : 3779 - 3788
  • [3] ALTERED SUBSTRATE-SPECIFICITY OF HERPES-SIMPLEX VIRUS THYMIDINE KINASE CONFERS ACYCLOVIR-RESISTANCE
    DARBY, G
    FIELD, HJ
    SALISBURY, SA
    [J]. NATURE, 1981, 289 (5793) : 81 - 83
  • [4] PATHOGENICITY IN MICE OF STRAINS OF HERPES-SIMPLEX VIRUS WHICH ARE RESISTANT TO ACYCLOVIR INVITRO AND INVIVO
    FIELD, HJ
    DARBY, G
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1980, 17 (02) : 209 - 216
  • [5] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
    FISCHL, MA
    RICHMAN, DD
    GRIECO, MH
    GOTTLIEB, MS
    VOLBERDING, PA
    LASKIN, OL
    LEEDOM, JM
    GROOPMAN, JE
    MILDVAN, D
    SCHOOLEY, RT
    JACKSON, GG
    DURACK, DT
    KING, D
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) : 185 - 191
  • [6] HAERTLE T, 1988, J BIOL CHEM, V263, P5870
  • [7] ACYCLOVIR PROPHYLAXIS AGAINST HERPES-VIRUS INFECTIONS IN SEVERELY IMMUNOCOMPROMISED PATIENTS - RANDOMIZED DOUBLE-BLIND TRIAL
    HANN, IM
    PRENTICE, HG
    BLACKLOCK, HA
    ROSS, MGR
    BRIGDEN, D
    ROSLING, AE
    BURKE, C
    CRAWFORD, DH
    BRUMFITT, W
    HOFFBRAND, AV
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 1983, 287 (6389): : 384 - 388
  • [8] INFECTION OF HTLV-III/LAV IN HTLV-I-CARRYING CELLS MT-2 AND MT-4 AND APPLICATION IN A PLAQUE-ASSAY
    HARADA, S
    KOYANAGI, Y
    YAMAMOTO, N
    [J]. SCIENCE, 1985, 229 (4713) : 563 - 566
  • [9] HUMAN IMMUNODEFICIENCY VIRUS (HIV) ANTIGENEMIA (P24) IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) AND THE EFFECT OF TREATMENT WITH ZIDOVUDINE (AZT)
    JACKSON, GG
    PAUL, DA
    FALK, LA
    RUBENIS, M
    DESPOTES, JC
    MACK, D
    KNIGGE, M
    EMESON, EE
    [J]. ANNALS OF INTERNAL MEDICINE, 1988, 108 (02) : 175 - 180
  • [10] KECKER RW, 1987, CLIN PHARMACOL THER, V41, P407
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