ANAPLASTIC THYROID-CARCINOMA WITH OSTEOSARCOMATOUS DIFFERENTIATION

被引：7
作者：
BLASIUS, S
EDEL, G
GRUNERT, J
BOCKER, W
SCHMID, KW
机构：
[1] UNIV MUNSTER, DEPT PATHOL, W-4400 MUNSTER, GERMANY
[2] UNIV MUNSTER, DEPT SURG, W-4400 MUNSTER, GERMANY
来源：
PATHOLOGY RESEARCH AND PRACTICE | 1994年 / 190卷 / 05期
关键词：
ANAPLASTIC THYROID CARCINOMA; OSTEOSARCOMA; IMMUNOHISTOCHEMISTRY;
D O I：
10.1016/S0344-0338(11)80217-7
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
A case of a thyroid tumour with the cytological and histological pattern of anaplastic carcinoma with extensive osteosarcomatous differentiation in a 54-year-old Kaukasian woman is presented. Immunohistochemical examination revealed keratin-vimentin co-expression in anaplastic tumour areas. According to the WHO classification of thyroid tumours the present tumour has to be classified as an anaplastic carcinoma. A retrospective survey revealed only twenty-four comparable cases in the literature. The present tumour most likely represents an example of a neoplastic epithelial-mesenchymal metaplasia. The possible mechanisms of the occurrence of thyroid tumours with mixed epithelial-mesenchymal differentiation are briefly discussed.
引用
收藏
页码：507 / 510
页数：4
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