EFFECT OF PROSTAGLANDIN E1 ON FOREARM BLOOD FLOW

被引：55

作者：

BEVEGARD, S

ORO, L

机构：

[1] Departments of Internal Medicine and Clinical Physiology, Thoracic Clinics, Karolinska Sjukhuset and King Gustav Vth Research Institute, Stockholm

来源：

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1969年 / 23卷 / 04期

关键词：

Blood flow; Intra-arterial infusion; Noradrenaline; Vasodilatation;

D O I：

10.3109/00365516909081700

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

In nine healthy male volunteers, the effect on forearm blood flow of infusions of prostaglandin E1 (PGE1) in the brachial artery was studied by means of strain-gauge plethysmography. PGE1 invariably caused a rapid local increase in blood flow with doses of 10-5 - 10-4 μg · min-1 · kg-1. With 10-2 μg · min-1 · kg-1 of PGE1, the forearm blood flow increased to an average of 30 ml · min-1 · 100 ml-1 (range 15-43). The PGE1-induced vasodilatation was not blocked by atropine or propranolol, but could be abolished by simultaneous infusion of noradrenaline. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：347 / &

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