Current perspectives in transplant medicine: hypothermic oxygenated perfusion

被引：4
作者：
Michel, Sebastian G. [1 ]
Madsen, Joren C. [2 ,3 ]
机构：
[1] Univ Munich, Dept Cardiac Surg, Munich, Germany
[2] Massachusetts Gen Hosp, Ctr Transplantat Sci, Dept Surg, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Dept Surg, Div Cardiac Surg, Boston, MA 02114 USA
来源：
TRANSPLANT RESEARCH AND RISK MANAGEMENT | 2016年 / 8卷
基金：
美国国家卫生研究院;
关键词：
organ transplantation; organ preservation; hypothermic perfusion;
D O I：
10.2147/TRRM.S91510
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
The purpose of this review was to provide an update on hypothermic oxygenated perfusion as a preservation technique for whole organ allografts. Clinical and experimental data in heart, lung, liver, kidney, and pancreas/islet transplantation are summarized with a special emphasis on marginal donors and donation after circulatory death. The rationale behind hypothermic machine perfusion as well as its advantages and disadvantages compared to conventional cold storage and the competing technique, normothermic machine perfusion, are reviewed.
引用
收藏
页码：25 / 30
页数：6
相关论文
共 53 条
[1]   HEMODYNAMICS AND METABOLISM OF THE INVIVO VASCULARLY ISOLATED CANINE PANCREAS [J].
ALTEVEER, RJ ;
JAFFE, MJ ;
VANDAM, J .
AMERICAN JOURNAL OF PHYSIOLOGY, 1979, 236 (06) :E626-E632
[2]   Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial [J].
Ardehali, Abbas ;
Esmailian, Fardad ;
Deng, Mario ;
Soltesz, Edward ;
Hsich, Eileen ;
Naka, Yoshifumi ;
Mancini, Donna ;
Camacho, Margarita ;
Zucker, Mark ;
Leprince, Pascal ;
Padera, Robert ;
Kobashigawa, Jon .
LANCET, 2015, 385 (9987) :2577-2584
[3]   Use of Ex Vivo Normothermic Perfusion for Quality Assessment of Discarded Human Donor Pancreases [J].
Barlow, A. D. ;
Hamed, M. O. ;
Mallon, D. H. ;
Brais, R. J. ;
Gribble, F. M. ;
Scott, M. A. ;
Howat, W. J. ;
Bradley, J. A. ;
Bolton, E. M. ;
Pettigrew, G. J. ;
Hosgood, S. A. ;
Nicholson, M. L. ;
Saeb-Parsy, K. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2015, 15 (09) :2475-2482
[4]   PRINCIPLES OF SOLID-ORGAN PRESERVATION BY COLD-STORAGE [J].
BELZER, FO ;
SOUTHARD, JH .
TRANSPLANTATION, 1988, 45 (04) :673-676
[5]   THE FUTURE OF KIDNEY-PRESERVATION [J].
BELZER, FO ;
SOUTHARD, JH .
TRANSPLANTATION, 1980, 30 (03) :161-165
[6]   SUCCESSFUL 17-HOUR PRESERVATION AND TRANSPLANTATION OF HUMAN-CADAVER KIDNEY [J].
BELZER, FO ;
ASHBY, BS ;
GULYASSY, PF ;
POWELL, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1968, 278 (11) :608-&
[7]   Machine perfusion for improving outcomes following renal transplant: current perspectives [J].
Cannon, Robert M. ;
Franklin, Glen A. .
TRANSPLANT RESEARCH AND RISK MANAGEMENT, 2016, 8 :1-7
[8]   Normothermic Ex Vivo Lung Perfusion in Clinical Lung Transplantation [J].
Cypel, Marcelo ;
Yeung, Jonathan C. ;
Liu, Mingyao ;
Anraku, Masaki ;
Chen, Fengshi ;
Karolak, Wojtek ;
Sato, Masaaki ;
Laratta, Jane ;
Azad, Sassan ;
Madonik, Mindy ;
Chow, Chung-Wai ;
Chaparro, Cecilia ;
Hutcheon, Michael ;
Singer, Lianne G. ;
Slutsky, Arthur S. ;
Yasufuku, Kazuhiro ;
de Perrot, Marc ;
Pierre, Andrew F. ;
Waddell, Thomas K. ;
Keshavjee, Shaf .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (15) :1431-1440
[9]   Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series [J].
Dhital, Kumud K. ;
Iyer, Arjun ;
Connellan, Mark ;
Chew, Hong C. ;
Gao, Ling ;
Doyle, Aoife ;
Hicks, Mark ;
Kumarasinghe, Gayathri ;
Soto, Claude ;
Dinale, Andrew ;
Cartwright, Bruce ;
Nair, Priya ;
Granger, Emily ;
Jansz, Paul ;
Jabbour, Andrew ;
Kotlyar, Eugene ;
Keogh, Anne ;
Hayward, Christopher ;
Graham, Robert ;
Spratt, Phillip ;
Macdonald, Peter .
LANCET, 2015, 385 (9987) :2585-2591
[10]   First Comparison of Hypothermic Oxygenated PErfusion Versus Static Cold Storage of Human Donation After Cardiac Death Liver Transplants An International-matched Case Analysis [J].
Dutkowski, Philipp ;
Polak, Wojciech G. ;
Muiesan, Paolo ;
Schlegel, Andrea ;
Verhoeven, Cornelia J. ;
Scalera, Irene ;
DeOliveira, Michelle L. ;
Kron, Philipp ;
Clavien, Pierre-Alain .
ANNALS OF SURGERY, 2015, 262 (05) :764-771
123456