TEST-TUBE EQUILIBRATION OF VOLATILE ANESTHETIC CONCENTRATIONS

被引:7
作者
MARTIN, DC [1 ]
PRUETT, JK [1 ]
ARONSTAM, RS [1 ]
机构
[1] MED COLL GEORGIA,DEPT PHARMACOL & TOXICOL,AUGUSTA,GA 30912
关键词
ANESTHETICS; VOLATILE; ENFLURANE; HALOTHANE; MEASUREMENT TECHNIQUES; INVITRO ASSAY;
D O I
10.1093/bja/70.3.365
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
We have measured concentrations of volatile anaesthetics after injection into test-tube assay solutions. In non-agitated tubes, aqueous anaesthetic concentrations decreased significantly throughout 40 min of incubation. Agitation (20-s vortex) of the tubes decreased the aqueous anaesthetic concentration by approximately 80% from concentrations in non-agitated tubes and resulted in more stable liquid anaesthetic concentrations over time. A decrease of less than 15% occurred between 10 and 50 min of incubation.
引用
收藏
页码:365 / 367
页数:3
相关论文
共 3 条
[1]   EQUILIBRATION OF HALOTHANE WITH BRAIN-TISSUE INVITRO - COMPARISON TO BRAIN CONCENTRATIONS DURING ANESTHESIA [J].
BAZIL, CW ;
RAUX, ME ;
YUDELL, S ;
MINNEMAN, KP .
JOURNAL OF NEUROCHEMISTRY, 1987, 49 (03) :952-958
[2]   HALOTHANE AND ISOFLURANE ALTER PHOSPHOLIPID TRANSMETHYLATION IN RAT-BRAIN SYNAPTOSOMES [J].
FRANKS, JJ ;
SASTRY, BVR ;
SURBER, MJ ;
ENGLAND, RE .
ANESTHESIOLOGY, 1990, 73 (05) :984-989
[3]  
IAIZZO PA, 1991, ANESTHESIOLOGY, V74, P531