PCR AMPLIFICATION OF VARIABLE SEQUENCE UPSTREAM OF KATG GENE TO SUBDIVIDE STRAINS OF MYCOBACTERIUM-TUBERCULOSIS COMPLEX

被引：32

作者：

GOYAL, M

YOUNG, D

ZHANG, Y

JENKINS, PA

SHAW, RJ

机构：

[1] ST MARYS HOSP,SCH MED,DEPT RESP MED,CHEST & ALLERGY CLIN,LONDON W2 1PG,ENGLAND

[2] ST MARYS HOSP,SCH MED,DEPT MED MICROBIOL,LONDON W2 1PG,ENGLAND

[3] UNIV WALES HOSP,PUBL HLTH LAB SERV,MYCOBACTERIUM REFERENCE UNIT,CARDIFF CF4 4XW,S GLAM,WALES

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1994年 / 32卷 / 12期

关键词：

D O I：

10.1128/JCM.32.12.3070-3071.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

PCR amplification of a species-specific 2-kb KpnI fragment of variable size located 10 kb upstream of the katG gene was used to subdivide 130 clinical isolates of Mycobacterium tuberculosis. Seven subtypes were identified, and their frequencies were distributed normally with respect to the size of the amplified product.

引用

收藏

页码：3070 / 3071

页数：2

相关论文

共 10 条

[1] STABILITY OF DNA FINGERPRINT PATTERN PRODUCED WITH IS6110 IN STRAINS OF MYCOBACTERIUM-TUBERCULOSIS [J].

CAVE, MD ;

EISENACH, KD ;

TEMPLETON, G ;

SALFINGER, M ;

MAZUREK, G ;

BATES, JH ;

CRAWFORD, JT .

JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (01) :262-266

[2] AN OUTBREAK OF MULTIDRUG-RESISTANT TUBERCULOSIS AMONG HOSPITALIZED-PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].

EDLIN, BR ;

TOKARS, JI ;

GRIECO, MH ;

CRAWFORD, JT ;

WILLIAMS, J ;

SORDILLO, EM ;

ONG, KR ;

KILBURN, JO ;

DOOLEY, SW ;

CASTRO, KG ;

JARVIS, WR ;

HOLMBERG, SD .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (23) :1514-1521

[3] EPIDEMIOLOGY OF AN OUTBREAK OF DRUG-RESISTANT TUBERCULOSIS IN THE UK USING RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISM [J].

GOYAL, M ;

ORMEROD, LP ;

SHAW, RJ .

CLINICAL SCIENCE, 1994, 86 (06) :749-751

[4] RESTRICTION-FRAGMENT-LENGTH-POLYMORPHISM ANALYSIS USING IS6110 AS AN EPIDEMIOLOGIC MARKER IN TUBERCULOSIS [J].

OTAL, I ;

MARTIN, C ;

VINCENTLEVYFREBAULT, V ;

THIERRY, D ;

GICQUEL, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (06) :1252-1254

[5] DNA FRAGMENT LENGTH POLYMORPHISM ANALYSIS OF MYCOBACTERIUM-TUBERCULOSIS ISOLATES BY ARBITRARILY PRIMED POLYMERASE CHAIN-REACTION [J].

PALITTAPONGARNPIM, P ;

CHOMYC, S ;

FANNING, A ;

KUNIMOTO, D .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (04) :975-978

[6] RAPID, AMPLIFICATION-BASED FINGERPRINTING OF MYCOBACTERIUM-TUBERCULOSIS [J].

PLIKAYTIS, BB ;

CRAWFORD, JT ;

WOODLEY, CL ;

BUTLER, WR ;

EISENACH, KD ;

CAVE, MD ;

SHINNICK, TM .

JOURNAL OF GENERAL MICROBIOLOGY, 1993, 139 :1537-1542

[7] MOLECULAR-CLONING OF A HIGHLY REPEATED DNA ELEMENT FROM MYCOBACTERIUM-TUBERCULOSIS AND ITS USE AS AN EPIDEMIOLOGIC TOOL [J].

ROSS, BC ;

RAIOS, K ;

JACKSON, K ;

DWYER, B .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (04) :942-946

[8] THE CATALASE PEROXIDASE GENE AND ISONIAZID RESISTANCE OF MYCOBACTERIUM-TUBERCULOSIS [J].

ZHANG, Y ;

HEYM, B ;

ALLEN, B ;

YOUNG, D ;

COLE, S .

NATURE, 1992, 358 (6387) :591-593

[9] TRANSFORMATION WITH KATG RESTORES ISONIAZID-SENSITIVITY IN MYCOBACTERIUM-TUBERCULOSIS ISOLATES RESISTANT TO A RANGE OF DRUG CONCENTRATIONS [J].

ZHANG, Y ;

GARBE, T ;

YOUNG, D .

MOLECULAR MICROBIOLOGY, 1993, 8 (03) :521-524

[10]

ZHANG Y, IN PRESS MOL MICROBI