CLINICAL-APPLICATIONS OF SOMATOSTATIN ANALOGS

被引：17
作者：
LAMBERTS, SWJ
KRENNING, EP
KLIJN, JGM
REUBI, JC
机构：
[1] ERASMUS UNIV, DEPT NUCL MED, 3000 DR ROTTERDAM, NETHERLANDS
[2] DR DANIEL DEN HOED CANC CTR, ROTTERDAM, NETHERLANDS
[3] SANDOZ RES INST, BERN, SWITZERLAND
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1990年 / 1卷 / 03期
关键词：
D O I：
10.1016/1043-2760(90)90025-X
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The somatostatin analog Sandostatin is successfully used in the treatment of metastatic endocrine pancreatic tumors, carcinoids, and acromegaly. In addition, somatostatin receptors are also present on other tumors in man, therefore making it possible to demonstrate these tumors by the administration of 123I-coupled to a somatostatin analog. © 1990.
引用
收藏
页码：139 / 145
页数：7
相关论文
共 33 条
[1]  
AARSEN RSR, 1987, ACTA ENDOCRINOL-COP, V116, P45
[2]  
BAUER W, 1982, LIFE SCI, V31, P1133, DOI 10.1016/0024-3205(82)90087-X
[3]   HYPOTHALAMIC POLYPEPTIDE THAT INHIBITS SECRETION OF IMMUNOREACTIVE PITUITARY GROWTH-HORMONE [J].
BRAZEAU, P ;
VALE, W ;
BURGUS, R ;
LING, N ;
BUTCHER, M ;
RIVIER, J ;
GUILLEMIN, R .
SCIENCE, 1973, 179 (4068) :77-79
[4]   PEPTIDES IN BRAIN - NEW ENDOCRINOLOGY OF NEURON [J].
GUILLEMIN, R .
SCIENCE, 1978, 202 (4366) :390-402
[5]   HETEROGENEITY OF GROWTH-HORMONE (GH) RELEASE BY INDIVIDUAL PITUITARY-ADENOMA CELLS FROM ACROMEGALIC PATIENTS, AS DETERMINED BY THE REVERSE HEMOLYTIC PLAQUE-ASSAY - EFFECTS OF SMS-201-995, GH-RELEASING HORMONE AND THYROTROPIN-RELEASING-HORMONE [J].
HOFLAND, LJ ;
VANKOETSVELD, PM ;
VANVROONHOVEN, CCJ ;
STEFANKO, SZ ;
LAMBERTS, SWJ .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 68 (03) :613-620
[6]   A PROSPECTIVE RANDOMIZED CONTROLLED CLINICAL-TRIAL COMPARING SOMATOSTATIN AND VASOPRESSIN IN CONTROLLING ACUTE VARICEAL HEMORRHAGE [J].
JENKINS, SA ;
BAXTER, JN ;
CORBETT, W ;
DEVITT, P ;
WARE, J ;
SHIELDS, R .
BRITISH MEDICAL JOURNAL, 1985, 290 (6464) :275-278
[7]  
KRENNING EP, 1989, LANCET, V1, P242
[8]   TREATMENT OF METASTATIC ISLET CELL-CARCINOMA WITH A SOMATOSTATIN ANALOG (SMS-201-995) [J].
KVOLS, LK ;
BUCK, M ;
MOERTEL, CG ;
SCHUTT, AJ ;
RUBIN, J ;
OCONNELL, MJ ;
HAHN, RG .
ANNALS OF INTERNAL MEDICINE, 1987, 107 (02) :162-168
[9]   TREATMENT OF THE MALIGNANT CARCINOID-SYNDROME - EVALUATION OF A LONG-ACTING SOMATOSTATIN ANALOG [J].
KVOLS, LK ;
MOERTEL, CG ;
OCONNELL, MJ ;
SCHUTT, AJ ;
RUBIN, J ;
HAHN, RG .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 315 (11) :663-666
[10]   THE SOMATOSTATIN ANALOG SMS 201-995 INDUCES LONG-ACTING INHIBITION OF GROWTH-HORMONE SECRETION WITHOUT REBOUND HYPERSECRETION IN ACROMEGALIC PATIENTS [J].
LAMBERTS, SWJ ;
OOSTEROM, R ;
NEUFELD, M ;
DELPOZO, E .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 60 (06) :1161-1165
1234