EXPERIMENTAL WORK WITH ISOXUPRINE FOR PREVENTION OF SKIN FLAP NECROSIS AND FOR TREATMENT OF THE FAILING FLAP

被引:38
作者
FINSETH, F [1 ]
ADELBERG, MG [1 ]
机构
[1] YALE UNIV,SCH MED,DIV PLAST & RECONSTRUCT SURG,NEW HAVEN,CT 06510
关键词
D O I
10.1097/00006534-197901000-00015
中图分类号
R61 [外科手术学];
学科分类号
摘要
The administration of isoxuprine intraperitoneally resulted in the complete survival of abdominal island skin flaps in rats that otherwise underwent a standard pattern of necrosis. The drug was effective when administered for two weeks before and one week after raising the flap, or when administered afterwards alone. The mechanisms of its action were investigated and are described. © 1979 American Society of Plastic Surgeons.
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页码:94 / 100
页数:7
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